Conferences, Lectures, & Seminars
Events for March
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BME 533 (Seminar in Biomedical Engineering)
Mon, Mar 05, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Natasha Lepore, USC Keck School of Medicine, Dept. of Radiology, BME & Children's Hospital Los Angeles
Talk Title: Methods for group analyses of neonatal brain MRI data
Biography: Natasha Lepore, Ph.D., Assistant Professor of Research in Radiology at USC and Children's Hospital
Los Angeles, with joint appointment in Biomedical Engineering
Computational anatomy, post-processing methods for structural and diffusion brain MR images, group analyses of normal and abnormal brain development and of brain neurological disorders in adults, genetic analyses in twins
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 (Seminar in Biomedical Engineering)Mon, Mar 19, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. John Troy, Northwestern University
Talk Title: Development and testing of a new patch clamp electrode system
Series: Invited Chair Series
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
USC Physical Sciences in Oncology Center Monthly Seminar
Fri, Mar 23, 2012 @ 11:45 AM - 01:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Alexander Anderson, Ph.D, Senior Member Moffitt Cancer Center
Talk Title: How Do Interactions Modulate Heterogeneity In Cancer Progression and Drug Resistance?
Abstract: The proteasome controls the concentrations of most proteins in the cytosol and nucleus of eukaryotic cells. The degradation signal or degron that targets proteins for proteolysis has two components, a proteasome binding tag, usually a poly-ubiquitin chain, and an initiation site in the form of an unstructured region in the substrate. The two degron components can function in trans when separated onto two different polypeptide chains so that a ubiquitinated adaptor can target a binding partner for proteolysis. Surprisingly, the initiation region contributes significantly to the specificity of Ubiquitin-Proteasome System. The length, location and amino acid sequence of initiation sites all affect whether a protein can be degraded or not. We define these rules in model systems and show how they apply to natural proteins. Once degradation has initiated, the proteasome normally digests its substrates processively to avoid the formation of fragments with undesirable activities. Interestingly, there are a few instances where this processivity breaks down and the proteasome generates partially degraded proteins. The partial degradation is caused by stop signals in the substrate proteins and we propose that this mechanism can explain steps in some signaling pathways and may involved in some neurodegenerative diseases.
Biography: Co-director of the Integrated Mathematical Oncology (IMO) department and Senior member at Moffitt Cancer Center. Dr. Anderson performed his doctoral work on hybrid mathematical models of nematode movement in heterogeneous environments at the Scottish Crop Research Institute in Dundee, UK. His postdoctoral work was on hybrid models of tumor-induced angiogenesis with Prof. Mark Chaplain at Bath University, UK. He moved back to Dundee in 1996 where he worked for the next 12 years on developing mathematical models of many different aspects of tumor progression and treatment, including anti-angiogenesis, radiotherapy, tumor invasion, evolution of aggressive phenotypes and the role of the microenvironment. He is widely recognized as one of only a handful of mathematical oncologists that develop truly integrative models that directly impact upon biological experimentation. His pioneering work using evolutionary hybrid cellular automata models has led to new insights into the role of the tumor microenvironment in driving tumor progression. Due to his belief in the crucial role of mathematical models in cancer research he moved his group to the Moffitt Cancer Center in 2008 to establish the Integrated Mathematical Oncology department.
Host: Center for Applied Molecular Medicine
Location: Harkness Auditorium #250
Audiences: Everyone Is Invited
Contact: kristina gerber
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 (Seminar in Biomedical Engineering)
Mon, Mar 26, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. Elizabeth Read,
Talk Title: Natural Immunity to HIV: Genetic Determinants versus Stochastic Dynamics
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor.
