Conferences, Lectures, & Seminars
Events for April
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BME 533 (Seminar in Biomedical Engineering)
Mon, Apr 02, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. Benjamin Cosgrove,
Talk Title: A more youthful self-renewal: Bioengineering approaches to rejuvenate dysfunctional muscle stem cells in aging
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 (Seminar in Biomedical Engineering)
Mon, Apr 09, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. Radha Kalluri, House Ear Institute
Talk Title: Acoustic emissions as probes of cochlear mechanics
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 (Seminar in Biomedical Engineering)
Mon, Apr 16, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Grodins Graduate Research Award Winner 2012, USC
Talk Title: TBA
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 (Seminar in Biomedical Engineering)
Mon, Apr 23, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. David Meany, University of Pennsylvania
Talk Title: Mechanoregulation of synaptic neurotransmission following traumatic brain injury
Abstract: Mechanical forces influence the development, maintenance, and degeneration of the nervous system at many length scales. At the synaptic scale, mechanical forces can play a role in the formation and maintenance of the synapse. One well studied synaptic receptor, the NMDA receptor (NMDAR), is considered important in regulating neuronal survival during disease or after injury. In this talk, we show the NMDA receptor is mechanosensitive, and this mechanosensitivity is a key aspect that underlies the role of the NMDA receptor in traumatic brain injury. The molecular domains of the NMDA receptor controlling mechanosensitivity are identified, and we use this molecular map to study how local synaptic signaling is modified following NMDAR mechanoactivation. Next, we use simulations of synaptic networks to identify how normal neurotransmission is altered following traumatic injury, and use these data to test the effectiveness of targeting NMDAR subpopulations for reducing neuronal death after injury. Consistent with predictions, results show that the most effective therapeutic approach is not a broad spectrum inhibition of the receptor, but a more targeted approach that stimulates synaptically localized receptors while inhibiting receptors localized extrasynaptically.
Host: BME Department
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
USC Physical Sciences in Oncology Center
Fri, Apr 27, 2012 @ 11:45 AM - 01:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. Mingming Wu, Associate Professor, Biological and Environmental Engineering Department, Cornell University
Talk Title: Microfluidics for Cancer Cell Chemotaxis
Abstract: The emerging field of micro-technology has opened up new possibilities for exploring cellular chemotaxis in real time and space, and at single cell resolution. Cancer cell chemotaxis plays important roles in cancer metastasis, where cancer cells break away from the primary tumors, migrate through the interstitial space, and establish secondary tumors at foreign sites. It is known that cells of many cancer types metastasize to lymph nodes. Despite its clinical importance, the physical and molecular cues that cancer cells use to navigate and migrate around lymph nodes are far from understood. In this talk, I will present efforts from my lab (biofluidics.bee.cornell.edu) in studying cancer cell migrating in well defined chemokine gradients, slow fluid flows (i.e. engineered interstitial flow), and biomatrix stiffness. We use microfluidic 3D in vitro model to provide physiologically realistic, 3D, microenvironment for cells, advanced imaging systems to follow cancer dynamics within a lymphoidal like environment. Using a malignant breast cancer cell line (MDA-MB-231) as a model system, we found that cancer cell migration is tightly controlled by the chemokine gradients, the compliance of the 3D biomatrix, and the intersitial fluid flows.
Biography: Mingming Wu received her PhD in Physics from the Ohio State University in the United States in 1992, and was a postdoctoral researcher in Ecole Polytechnique, France in year 1992 and University of California at Santa Barbara in 1993- 1995. In year 1996, she joined the physics department at Occidental College in Los Angeles as an assistant/associate professor. Since 2003, she is an adjunct associate professor in the engineering college at Cornell University. Her current research interests are: Bio-inspired engineering, microfluidics and quantitative imaging. Her role in the PS-OC center is to use advanced imaging, as well as micro-fabrication techniques to explore dynamic processes in cancer metastatic cascades.
Host: Center for Applied Molecular Medicine
More Information: USC-PSOC_MonthlySeminar.pdf
Location: Clinical Science Center (CSC) - Harkness Auditorium
Audiences: Everyone Is Invited
Contact: Kristina Gerber
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor.
