Conferences, Lectures, & Seminars
Events for April
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Seminars in Biomedical Engineering
Mon, Apr 01, 2013 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Mehmet Akcakaya, Ph.D., Instructor in Medicine, Harvard Medical School Senior Research Scientist, Cardiac MR Center, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA
Talk Title: Acceleration Methods for High-Resolution Cardiac MRI Using Compressed Sensing
Host: Biomedical Engineering
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
Seminars in Biomedical Engineering
Mon, Apr 08, 2013 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Donald Arnold, Ph.D. USC, Associate Professor Department Molecular Biology Division Dornsife College of Letters, Arts and Sciences University of Southern California
Talk Title: Now you see 'em, Now you don't: New molecular tools for visualizing and ablating endogenous proteins in living cells.
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
Seminars in Biomedical Engineering
Mon, Apr 15, 2013 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Jay Lieberman, MD (USC), Professor and chair of the Department of Orthopaedic Surgery, Keck School of Medicine of USC, Orthopaedist-in-Chief at the Keck Medical Center of USC
Talk Title: Tissue Engineering for Bone Repair: Progenitor Cell Response to Bone Graft Substitutes
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
Biomedical Engineering Seminars (BME 533)
Mon, Apr 22, 2013 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Heidi Gensler, BME, Graduate Research Assistant, Biomedical Microsystems Laboratory , Advisor: Ellis Meng; Winner of BME's highest award for PhD students, the Grodins Graduate Award (2013)
Talk Title: A Wireless Implantable MEMS Micropump System for Site-specific Anti-cancer Drug Delivery
Host: David D'Argenio
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
USC Physical Sciences in Oncology Seminar
Fri, Apr 26, 2013 @ 11:45 AM - 01:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: DEAN FELSHER M.D., PH.D. , Professor of Medicine-Oncology, Pathology and Molecular Imaging, Department of Medicine, Stanford University
Talk Title: Modeling and Predicting Oncogene Addiction
Abstract: Cancers are largely caused by the activation of oncogenes. We have developed an experimental system to model and predict the therapeutic efficacy of targeted therapy of oncogenes. Using the Tet system, we can conditionally regulate oncogene expression in vivo in a temporally controlled and tissue specific manner. We have shown that many oncogenes (MYC, RAS, BCR-ABL) induce tumorigenesis that is completely reversible upon their inactivation. We have described this phenomena as oncogene addiction. Oncogene addiction is associated with proliferative arrest, apoptosis, differentiation, cellular senescence and the shutdown of angiogenesis. The specific consequences of oncogene inactivation depend both on the genetic and cellular context. In some cases, even brief inactivation of an oncogene can result in sustained tumor regression. In other cases, oncogene inactivation is associated with tumor dormancy. Tumor cell intrinsic and host-dependent cell autonomous mechanisms are involved. Tumor cell intrinsic mechanisms appear to involve mechanisms that are dependent upon DNA repair processes, the regulation of protein synthesis and of cellular metabolism. Host-dependent mechanisms include the regulation of angiogenesis and immune cell elimination. In addition, tumor cells secrete autocrine factors critical to oncogene addiction. We have uncovered that oncogene addiction is not cell autonomous and requires an intact host immune system. Specifically, CD4+ T-cells are required for MYC or BCR-ABL inactivation to induce sustained tumor regression. We have found that in the absence of an immune system, oncogene inactivation failed to both induce cellular senescence in tumor cells as well as to shut down angiogenesis in the host. Finally, our experimental model system can be used to model Oncogene Addiction. We have shown that we can use simple mathematical model to predict the therapeutic consequences of oncogene inactivation.
Biography: USC was selected to establish a $16 million cancer research center as part of a new strategy against the disease by the U.S. National Institutes of Health and its National Cancer Institute. The new center is one of 12 in the nation to receive the designation. During the five-year initiative, the Physical Sciences-Oncology Centers will take new, nontraditional approaches to cancer research by studying the physical laws and principles of cancer; evolution and the evolutionary theory of cancer; information coding, decoding, transfer and translation in cancer; and ways to de-convolute cancer's complexity. As part of the outreach component of this grant, the Center for Applied Molecular Medicine is hosting a monthly seminar series.
Host: USC Physical Sciences in Oncology Center
Location: Clinical Science Center (CSC) - #250
Audiences: Everyone Is Invited
Contact: Kristina Gerber
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
Biomedical Engineering Seminars (BME 533)
Mon, Apr 29, 2013 @ 12:30 PM - 01:30 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Samantha Holdsworth, Bammer Group Manager, Center for Quantitative Neuroimaging Research Associate, Lucas MRS/I Center Department of Radiology, School of Medicine, Stanford University
Talk Title: High Resolution Neuroimaging
Host: Biomedical Engineering
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor.
