Conferences, Lectures, & Seminars
Events for November
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BME 533 - Seminar in Biomedical Engineering
Mon, Nov 01, 2010 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Natasha Leporé, Department of Radiology, Childrens Hospital Los Angeles
Talk Title: Methods for group analyses of brain magnetic resonance data
Host: Department of Biomedical Engineering, USC
More Info: http://bme.usc.edu/assets/007/71621.pdfLocation: Olin Hall of Engineering (OHE) - 132
Audiences: BME graduate students, Faculty, contact department if interested (213-740-7237)
Contact: Mischalgrace Diasanta
Event Link: http://bme.usc.edu/assets/007/71621.pdf
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 - Seminar in Biomedical Engineering
Mon, Nov 08, 2010 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Gerald Loeb, Department of Biomedical Engineering, USC
Talk Title: Biomimetic Tactile Sensing for Prosthetic and Robotic Hands
Host: Department of Biomedical Engineering, USC
Location: Olin Hall of Engineering (OHE) - 132
Audiences: BME graduate students, Faculty, contact department if interested (213-740-7237)
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 - Seminar in Biomedical Engineering
Mon, Nov 15, 2010 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Hossein Jadvar, Department of Radiology, USC Keck School of Medicine,
Talk Title: Promise of Molecular Imaging
Host: Department of Biomedical Engineering, USC
Location: Olin Hall of Engineering (OHE) - 132
Audiences: BME graduate students, Faculty, contact department if interested (213-740-7237)
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
USC PSOC Monthly Seminar Series - Dr. Timothy Newman
Fri, Nov 19, 2010 @ 11:45 AM - 01:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Dr. Timothy Newman, Professor of Physics, Physical Sciences, Director of Center for Biological Physics, Arizona State University
Talk Title: Modeling Active Processes in Cancer Progression and Embryogenesis
Abstract: Our group focuses on the study of multicellular dynamics, mainly through the use of large-scale computation. Our work is split evenly between two profoundly challenging yet distinct problems: embryo development and cancer. The Subcellular Element Model (ScEM ) we have developed allows for the simulations of large numbers of deformable three-dimensional cells in a grid-free setting. Briefly, each cell is described by a few hundred "subcellular elements" which represent the nodes of a coarse-grained cytoskeleton. Elements are visco-elastically coupled with short-range interactions. Neighboring cells interact through short-ranged interactions between peripheral elements on each cell. This algorithm allows a computationally efficient means to simulate three-dimensional cell shape and deformations. Despite the simplicity of its underlying framework, the ScEM has been shown to reproduce the basic rheological properties of cells on times scales greater than ~ 0.1s (Sandersius and Newman 2008). We are developing new modules for ScEM, building on the basic biomechanical foundation of the model. In particular, we are modeling active cell dynamics (e.g. polarization, cytoskeletal rearrangement) in order to capture important features of cell movement within tissue. I will discuss our recent work on adding layers of active cell behavior to the underlying model of cell mechanics, and how this has enabled us to describe gross cell deformations under applied stress, as well as fluid-like motions which are commonly seen in embryonic epithelia. I will also address the challenges in applying this methodology to modeling multicellular systems relevant to cancer progression.
Hosted by Center for Applied Molecular Medicine. For additional information, contact: glenda.redfield@med.usc.edu or 323-442-3849. Pizza and beverages will be provided at 11:45 a.m.
Host: Center for Applied Molecular Medicine
Location: May Ormerod Harris Hall, Quinn Wing & Fisher Gallery (HAR) - -kness Auditorium IGM
Audiences: Everyone Is Invited
Contact: Glenda Redfield
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 - Seminar in Biomedical Engineering
Mon, Nov 22, 2010 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Harvey Borovetz, Department of Bioengineering, U. Pittsburgh
Talk Title: Current & Future Perspectives in Cardiac Assist Devices for Adult and Pediatric Patients
Biography: http://www.engr.pitt.edu/bioengineering/main/people/faculty/borovetz_harvey.html
Host: Department of Biomedical Engineering, USC
Location: Grace Ford Salvatori Hall Of Letters, Arts & Sciences (GFS) - 106
Audiences: BME graduate students, Faculty, contact department if interested (213-740-7237)
Contact: Mischalgrace Diasanta
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor. -
BME 533 - Seminar in Biomedical Engineering
Mon, Nov 29, 2010 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Paul Yager, Chair of the Department of Bioengineering, University of Washington
Talk Title: Microfluidics 2.0: 2-Dimensional Paper Networks for POC Diagnostics in the Developed and Developing Worlds
Abstract: Diagnosis of disease in the developing world is, today, not as well supported by technology as it is in the developed world. A team consisting of the University of Washington, Epoch Biosciences, PATH, and Micronics, Inc., has just completed a 5-year project for developing a point-of-care system for diagnosing infectious diseases at the point-of-care in the developing world. The DxBox, as the prototype was called, was based on a permanent battery-powered reader, and polymer-based disposable microfluidic cards that contain all reagents (dry and wet). Commercial versions of this instrument will bring new capabilities for multiplexed analysis by both immunoassays and nucleic acid amplification to locations that could never support such analysis before.
The problem is that to date all flexible microfluidic systems, including the DxBox disposables, have required supporting technology at least to move fluid through the channels, including syringe pumps, or pressure sources and valves, heaters and voltage sources. This equipment has proven to be irreducibly expensive. In contrast, paper-based lateral flow immunoassays (or immunochromatographic test strips) are used in the home in the developed world (e.g., pregnancy test strips) and in the developing world for point of-care detection of infectious disease. These strips can be inexpensive, because they use only capillarity to move fluids; they require no supporting pumps or pressure sources or readers, and they are well suited to storage of reagents in dry form. However, they often measure only one analyte per strip, and are limited to high-concentration analytes because they can only perform a limited sequence of reactions, and usually provide only qualitative results.
Based on immunoassays for the DxBox on nitrocellulose devices and the work of others who have demonstrated some abilities of paper networks, it is now clear that one can combine the sophistication of the microfluidic circuit with the pump-free simplicity of capillary pumping. Under NIH support, we have been focusing on development of sophisticated but disposable 2-dimensional porous (or paper) networks (2DPNs) that allow programmed sequential delivery of an arbitrarily large set of reagents to specific sites on the devices. This offers the promise of the sophistication of microfluidic systems with no supporting instrument at all, except for a cell phone camera. By limiting the devices as much as possible to single layer of porous material (plus an injection-molded housing), cost can be extremely low. As a first challenge, we are targeting a high-value applicationâthe development of multiplexed immunoassays that are made more sensitive than conventional lateral flow devices by performing chemical and biochemical amplification.
The first challenge was to develop design tools for 2DPNs, coupled with methods for monitoring flow in the opaque 2DPN matrix. We have also demonstrated the several conventional microfluidic devices can be implemented in 2DPNs with excellent performance, but at ~104 times less cost. We have shown that 2DPNs allow automated instrument-free sequential delivery of reagents in a format ideally suited to inexpensive disposables, and have extended this to amplification chemistries, achieving much higher sensitivity without the need for a specialized reader.
Host: Department of Biomedical Engineering, USC
More Info: http://faculty.washington.edu/yagerp/Location: Ethel Percy Andrus Gerontology Center (GER) - Auditorium
Audiences: BME graduate students, Faculty, contact department if interested (213-740-7237)
Contact: Mischalgrace Diasanta
Event Link: http://faculty.washington.edu/yagerp/
This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor.
