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Events for April 20, 2015
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CS Colloquium: Joyce Ho (UT-Austin) - Extracting medically interpretable concepts from complex health data
Mon, Apr 20, 2015 @ 11:00 AM - 12:00 PM
Thomas Lord Department of Computer Science
Conferences, Lectures, & Seminars
Speaker: Joyce Ho , UT-Austin
Talk Title: Extracting medically interpretable concepts from complex health data
Series: CS Colloquium
Abstract: Electronic health records (EHRs) are an increasingly important source of patient information. However, a major challenge is how to transform EHR into meaningful concepts so domain experts can act on the information in an appropriate manner. In this talk, I will discuss two approaches to extract concise, meaningful concepts from certain types of health datasets. First, I will describe a dynamic time series model that tracks a patient's cardiac arrest risk based on physiological measurements. Our algorithm is inspired by financial econometric and yields interpretability and predictability of a cardiac arrest event. Next, I will present sparse, nonnegative tensor factorization models to obtain multiple medical concepts with minimal human supervision. Tensor factorization utilizes information in the multiway structure to derive concise latent factors even with limited observations. Experimental results on real EHRs demonstrate the effectiveness of our models to extract medically interpretable concepts from complex health data.
Biography: Joyce Ho is a PhD Candidate in the Electrical and Computer Engineering Department at the University of Texas at Austin co-advised by Dr. Joydeep Ghosh and Dr. Sriram Vishwanath. Her research involves the development of novel data mining and machine learning algorithms to address problems in healthcare. Joyce has also co-founded a healthcare data analytics company, Accordion Health, which was awarded an NSF Small Business Innovation Research (SBIR) grant.
Host: Prof. Yan Liu
Location: Henry Salvatori Computer Science Center (SAL) - 322
Audiences: Everyone Is Invited
Contact: Assistant to CS chair
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Seminar in Biomedical Engineering
Mon, Apr 20, 2015 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Michael Anthony Bonaguidi, PhD, Assistant Professor of Stem Cell Biology & Regenerative Medicine
Talk Title: Neural Stem Cells: New Tools Identify Dynamic Origins of Adult Brain Plasticity
Abstract: The adult mammalian brain has the remarkable capability to undergo structural changes by adding newborn cells to selected existing circuitry. Understanding cellular origins and mechanistic regulation of this neural plasticity serves as a model of endogenous regenerative potential. We developed a noninvasive genetic strategy to reveal the basic properties of individual neural stem cells within the adult hippocampus and how neural circuitry couples their behavior with specific tissue demands. Recent computational and systems level approaches provide evidence for the co-existence of neural stem cells with distinct molecular and behavioral identity. A vision of how diverse stem cells adapt and repair the brain will be discussed.
Biography: Biosketch
Michael Bonaguidi, PhD, joined USC as an assistant professor in the Department of Stem Cell Biology and Regenerative Medicine in January 2015 and holds associate membership in the Zilkha Neurogenetic Institute. He received his bachelorâs degree in Biomedical Engineering from Marquette University, PhD in neuroscience from Northwestern University and completed his postdoctoral training at the Johns Hopkins Institute for Cell Engineering. His group investigates brain development, adaptation and aging with the overall goal of identifying and overcoming limits of neural regeneration. They provided evidence of individual stem cell existence within the adult brain. By developing a new visualization approach, they found that these stem cells spawn more stem cells, and form new neurons and critical supporting cells called astroglia. Their subsequent studies have linked adaptation of neural stem cell behavior to changes in the brain under normal conditions and during injury. These stem cells offer intriguing possibilities for treating a variety of conditions, including mood disorders, deficits in social adaptation and brain damage. He has published in high-impact journals such as Cell, Nature, Cell Stem Cell and Nature Neuroscience and received prestigious awards, most recently the NIH Pathway to Independence Fellowship.
Research Impact:
The Bonaguidi Laboratory investigates how stem cells act to adapt and repair the adult brain. Using endogenous neural stem cells as a model system, their approach incorporates principles from neuroscience, single cell molecular and cellular biology, computational and systems biology, imaging and engineering to unravel brain plasticity. The laboratory focuses on the reciprocal interaction between neural stem cells and their surroundings in normal, aging, injured and diseased states. The long-term goal is to evaluate the capacity of endogenous stem cells to serve as a cellular mediator of neural function and as a therapeutic source of cognitive rejuvenation.
Host: Stanley Yamashiro
Location: OHE 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
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Munich Graduate Information Session
Mon, Apr 20, 2015 @ 07:00 PM - 09:00 PM
Viterbi School of Engineering Graduate Admission
Workshops & Infosessions
Students who have earned or are in the process of earning a Bachelor's degree in engineering, math, or a hard science (such as physics, biology, or chemistry) are welcome to attend to learn more about applying to our graduate programs.
The session will include information on the following topics:
Master's & Ph.D. programs in engineering
How to Apply
Scholarships and funding
Student life at USC and in Los Angeles
There will also be sufficient time for questions. Refreshments will be provided.
Please contact us at viterbi.gradprograms@usc.edu if you have any inquiries about the event.
In order to guarantee seating availability, we request completion of the online registration form using the Eventbrite links on the event pageAudiences: Students with an undergraduate background in engineering, math or science
Contact: William Schwerin
