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SUNMONTUEWEDTHUFRISAT
Events for April 21, 2008
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Noah Malmstadt, Assistant Professor of Chemical Engineering and Materials Science, USC
Mon, Apr 21, 2008 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Nanoscale structure formation in biomimetic cell membranes
Audiences: Department Only
Contact: Mischalgrace Diasanta
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The Timing of Testing and Treatment of Hepatitis C
Mon, Apr 21, 2008 @ 02:00 PM - 03:00 PM
Daniel J. Epstein Department of Industrial and Systems Engineering
University Calendar
Daniel J. Epstein Department of Industrial and Systems Engineering Seminar"The Timing of Testing and Treatment of Hepatitis C"Daniel Mello FaissolDoctoral Student, H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of TechnologyABSTRACT: Hepatitis C virus (HCV) is a blood-borne disease present in 3.9 million people in the US that can cause end stage liver disease. It is the leading cause of liver transplants and the 10th leading cause of death in the US. It is generally asymptomatic for decades. Almost 50% of those infected are unaware of the presence of the disease, many remaining unaware until end stage liver disease begins and treatment is no longer effective. Our goal is to determine the best testing policy for HCV where treatment is an option. Critical components include the possibility of multiple tests and the allowance for awareness of the disease to change behavior, such as secondary transmissions and alcohol consumption, which effects disease progression. We develop a Markov Decision Process (MDP) model for diseases that incorporates disease transmission, testing, treatment and the natural history of the disease. We populate the model with data from the medical literature and compare our findings to current HCV screening recommendations.MONDAY, APRIL 21, 2008, GERONTOLOGY BUILDING (GER) ROOM 309, 2:00 – 3:00 PM
Location: Ethel Percy Andrus Gerontology Center (GER) - 309
Audiences: Everyone Is Invited
Contact: Georgia Lum
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BME Weekly Seminar Series-Rehabilitation for the Self-Management of Parkinsons Disease
Mon, Apr 21, 2008 @ 04:00 PM - 05:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
OBJECTIVE: To determine whether rehabilitation that focuses on self-management of health helps to improve the day-to-day functioning and quality of life of community-living clients with Parkinson's disease (PD), beyond the effects of medical treatment alone. DESIGN: In a randomized controlled design, 120 participants were assigned to one of three conditions for a duration of 6 weeks: (I) medication only, (II) medication plus 2 outpatient group rehabilitation sessions and 1 social activity session per week, or (III) medication plus 2 outpatient group rehabilitation sessions and 1 home/community rehabilitation session per week. Rehabilitation occurred through integrated physical, occupational, and speech therapy services specialized to the self-management of health needs of people with PD. RESULTS: Compliance with treatment was 93% in the outpatient setting and 99% in the home setting. The first specific aim of the study was to determine if increasing "doses" of self-management rehabilitation (from Conditions I to II to III) resulted in increasingly positive quality of life outcomes. The results support this dose effect (F(1,111) = 5.96, p = .005). With increasing doses of rehabilitation, individuals experienced increasingly positive quality of life outcomes as measured by the Parkinson's Disease Questionnaire- 39. DISCUSSION: These results are consistent with the findings from the meta-analyses and the previous randomized controlled trial conducted by our research group. The primary hypothesis of this study was supported: there was a linear increase in immediate post-intervention improvement in overall quality of life from optimal medication (Condition I) to the addition of18 hours of self-management rehabilitation (Condition II) to 27 hours of self-management rehabilitation (Condition III) administered over a six-week period. These effects were strongest immediately following intervention and persisted to a smaller degree at 6 months follow-up. For more information, please visit http://www.bu.edu/sargent/centers/research/neurorehab/team/index.shtmlThe seminar is simultaneously presented at UPS and HSC, and available via live Web Cast at:http://capture.usc.edu/college/Catalog/?cid=af180d48-ceff-42b9-a35c-eb199daed320Information about all seminars can be found at: http://bme.usc.edu/valero/seminar.htm
Location: HSC: B16 Basement of the Norris Medical Library ; UPC: Ahmanson Center for Biological Research (ACB)
Audiences: Faculty and Graduate Students
Contact: Toyicha Chisom
