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SUNMONTUEWEDTHUFRISAT
Events for May 17, 2013
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AI Seminar
Fri, May 17, 2013 @ 11:00 AM - 12:00 PM
Information Sciences Institute
Conferences, Lectures, & Seminars
Speaker: Gully Burns, Project Leader. ISI
Talk Title: Introducing paradigms as a viable structural guide for biomedical knowledge engineering
Abstract: Following Thomas Kuhn's seminal 1962 book in which he introduced the notion of scientific paradigms, we here describe a computational methodology that leverages that concept in a concrete formulation. I describe this approach partially as a methodology for framing and scoping the knowledge representation and analysis work necessary to build tools to serve a specific community. However this approach also has technical implications that are relevant to semantic web representations, the use of workflows and reasoning and the way that we derive content from existing scientific artefacts. We will explore this viewpoint in the context of a well defined domain problem (Biomarker studies of neurodegenerative diseases) with the strategic intent of developing a practical, scoped view of biomarker data that could serve as the basis of corollary work within AI computer science groups.
Biography: Gully Burns develops pragmatic biomedical knowledge engineering systems for scientists that (a) provide directly useful functionality in their everyday use and (b) is based on innovative, cutting edge computer science that subtlely transforms our ability to use knowledge. He was originally trained as a physicist at Imperial College in London before switching to do a Ph.D. in neuroscience at Oxford. He came to work at USC in 1997, developing the 'NeuroScholar' project in Larry Swanson's lab before joining the Information Sciences Institute in 2006. He is now works as project leader in ISI's Information Integration Group, as well as a Research Assistant Professor of neurobiology at USCââ¬â¢s College of Letters, Arts and Sciences. He maintains a personal blog called 'Ars-Veritatis, the art of truth', and is very interested in seeing how his research in developing systems for scientists could translate to helping and supporting understanding and our use of knowledge in everyday life.
Host: David Chiang
More Info: http://www.isi.edu/technology_groups/insy/home
Webcast: TBALocation: Information Science Institute (ISI) - 11th floor conference room
WebCast Link: TBA
Audiences: Everyone Is Invited
Contact: Kary LAU
Event Link: http://www.isi.edu/technology_groups/insy/home
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USC Physical Sciences in Oncology Seminar Series
Fri, May 17, 2013 @ 11:45 AM - 01:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Larry Smarr, Ph.D., University of California, San Diego
Talk Title: Tracking Immune Biomarkers and the Human Gut Microbiome: Inflammation, Crohn's Disease, and Colon Cancer
Abstract: Colon Cancer is the most common cancer among Inflammatory Bowel Disease (IBD) patients and IBD is one of the three leading high-risk factors for Colon Cancer. In 2012 it was found, by using genetic sequencing of the gut microbiome, that Fusobacteria sequences were enriched in colorectal carcinomas (CRC). To explore this possible link between inflammation, gut microbes, and colon cancer I have turned my own body into a "genomic observatory." I have been tracking over 100 blood/stool biomarkers in my own body every few months for the last five years, with a focus on immune variables. Using key biomarkers and imaging technologies I diagnosed myself as having late-onset Crohn's Disease, one of the two forms of IBD. Besides obtaining one million SNPs of my human genome, I have collaborated with the J. Craig Venter Institute to metagenomically sequence my gut microbiome at three different times during a period of high inflammation. My microbiome was compared with 50 other subjects, sequenced by the NIH Human Microbiome Project--35 healthy and the remainer with IBD. I discovered that at the height of my inflammation (CRP~30), I had 8% relative abundance of Fusobacteria, 40x healthy subjects. Following antibiotic/corticosteroid therapy the Fusobacteria were reduced 90-fold. The next step is to move to high-throughput integrated personal "omics" to refine the host-microbiome dynamics. With these new tools of computationally-intensive omics, there is a hope that we will gain new insights into the pathogenisis of CRC.
Biography: USC was selected to establish a $16 million cancer research center as part of a new strategy against the disease by the U.S. National Institutes of Health and its National Cancer Institute. The new center is one of 12 in the nation to receive the designation. During the five-year initiative, the Physical Sciences-Oncology Centers will take new, nontraditional approaches to cancer research by studying the physical laws and principles of cancer; evolution and the evolutionary theory of cancer; information coding, decoding, transfer and translation in cancer; and ways to de-convolute cancer's complexity. As part of the outreach component of this grant, the Center for Applied Molecular Medicine is hosting a monthly seminar series.
Host: USC PSOC
More Information: USC-PSOC_MonthlySeminar.pdf
Location: Elaine Stevely Hoffman Medical Research Center (HMR) - Hastings Auditorium, 1st Floor
Audiences: Everyone Is Invited
Contact: Kristina Gerber
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2013 Computer Science Commencement Reception
Fri, May 17, 2013 @ 12:00 PM - 03:00 PM
Thomas Lord Department of Computer Science
Receptions & Special Events
Dear Graduation Class,
You are cordially invited to attend the official
Computer Science Commencement Reception
of the Class of 2013,
to be held at the Salvatori Lawn (Located between SAL and PHE),
on Friday, May 17th, from 12:00-3:00 p.m.
Please RSVP By 5:00p.m. on Wednesday, May 10th if you and guest(s) (limit four) will be attending. Wristbands are required to enter Computer Science Reception. Once you have RSVP’d wristbands can be picked up at SAL 300 receptionist starting 9:00 a.m. on Monday, May 13th, 2013.Location: Henry Salvatori Computer Science Center (SAL) -
Audiences: Everyone Is Invited
Contact: Assistant to CS chair
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Qing Dou- NL Seminar: "Deciphering Gigaword:"
Fri, May 17, 2013 @ 03:00 PM - 04:00 PM
Information Sciences Institute
Conferences, Lectures, & Seminars
Speaker: Qing Dou, USC/ISI
Talk Title: Deciphering Gigaword
Series: Natural Language Seminar
Abstract: Abstract: State of the art machine translation systems learn translation rules from large amounts of parallel data (pairs of sentences that are translation of each other). Unfortunately, the amount of parallel data is very limited for many languages and domains. In general, it is easier to obtain monolingual data. Is it possible to learn useful translations from large amounts of monolingual data to improve machine translation when the amount of parallel data is limited? In this talk, I will present my ongoing work that applies decipherment techniques to decipher hundreds of millions Spanish news texts into English and learns a translation lexicon from the decipherment to improve a translation model learned from limited parallel data.
Biography: Home Page:http://www.isi.edu/~qdou/qdou_cv.pdf
More Info: http://nlg.isi.edu/nl-seminar/
Location: Information Science Institute (ISI) - 11th Flr Conf Rm # 1135
Audiences: Everyone Is Invited
Contact: Peter Zamar
Event Link: http://nlg.isi.edu/nl-seminar/
