Select a calendar:
Filter May Events by Event Type:
SUNMONTUEWEDTHUFRISAT
Events for May 21, 2010
-
Physical Sciences for Optical Molecular Imaging in Oncology - Adventures in the Translational Woods
Fri, May 21, 2010 @ 01:00 PM - 02:30 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
The USC Center for Applied Molecular Medicine, as part of the Physical Sciences in Oncology Center, is proud to present Dr. Daniel L. Farkas, Professor of Surgery and Biomedical Sciences, Director, Minimally Invasive Surgical Technologies Institute, Cedars-Sinai Medical Center, and Research Professor, Biomedical Engineering, USC.ABSTRACT:
In order to see the bench-to-bedside dream for translational research become a reality, we need to develop approaches that, while technologically sophisticated, allow deployment into a clinical setting. Our focus area is where light and patient meet, and improvements that yield better outcomes, by identifying and addressing the obstacles preventing the timely clinical adoption of laboratory-based advances. The unifying themes of our efforts can be summarized as follows: Surgery is still the main treatment for most major diseases, and it is moving rapidly towards minimally invasive intervention, requiring new approaches. Biophotonics represents a major new area of hope and growth for this type of high-tech intervention. The move of useful laboratory-derived knowledge into clinical practice has been hampered by a number of issues, not the least of which is the difficulty of detecting, characterizing and monitoring very small entities (molecules, cells) within the human body, especially quantitatively and dynamically. New tools and strategies are needed, with likely new outcomes. Ours is a multi-level, multimode approach to biomedical optical imaging, optimized for earlier and more reproducible detection of abnormalities and for a tighter spatio-temporal coupling between such diagnosis and intervention. This talk will concentrate on our cancer research work, and will review recent examples (physical sciences-based) optical bioimaging advances yielding a new armamentarium, by biological organization level (cellular; tissue; preclinical; and clinical/human domains, respectively). Results presented will be representative of both translational challenges and their technical solutions, and of some major application areas. The types of cancer highlighted will include breast, lung, bladder, prostate, brain, and melanoma. The methods include spectral reflectance, autofluorescence; optical coherence tomography; hyper-spectral Mie (elastic) scattering imaging for endoscopic guidance; non-linear (multiphoton) and lifetime imaging; design and use of multimode imaging devices, nano(photo)medicine, and photodynamic therapy for chemotherapy and its assessment. A new, technologically heightened operating room design for deploying these translational methods will also be discussed.
Location: May Ormerod Harris Hall, Quinn Wing & Fisher Gallery (HAR) - kness Auditorium - HSC, CSC -240
Audiences: Everyone Is Invited
Contact: Yvonne Suarez
