Events Calendar

Arterial Spin Labeled Perfusion MRI and Dynamic MRA

Speaker: Prof. Danny J.J. Wang , University California, Los Angeles

Talk Title: Arterial Spin Labeled Perfusion MRI and Dynamic MRA

Series: Medical Imaging Seminar Series

Abstract: Arterial spin labeling (ASL) is an emerging MRI technique for noninvasive measurement of microvascular blood flow or perfusion as well as for non-contrast enhanced MR angiography (MRA). ASL is appealing for noninvasive evaluation of vascular function of the brain and body organs. However, its widespread clinical applications have been hampered by the relatively low SNR and the competing effects of T1 relaxation and the transit time required for the labeled blood to reach the target tissue. During the past decade, many technical advancements in MRI have been utilized to enhance the SNR and reliability of ASL, including high and ultrahigh magnetic field, parallel imaging, pseudo-continuous spin labeling, and highly efficient pulse sequences for image acquisition (e.g. 3D GRASE, multi band and dynamic golden angle radial acquisition). In this presentation, I will review the latest technical developments in ASL perfusion MRI and non-contrast enhanced dynamic MRA along with their clinical applications in stroke, arteriovenous malformation (AVM), brian tumor, dementia and neurodevelopmental disorders.

Biography: Dr. Wang obtained his PhD in Biophysics from the Lab of Cognitive Brain Imaging, University of Science & Technology of China (now Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences) in 1998. He subsequently obtained postdoctoral training in MRI biophysics at University of Pennsylvania from 1999 to 2002. He has been a Research Assistant Professor at the Departments of Radiology and Neurology, University of Pennsylvania from 2003 to 2010. He joined Ahmanson-Lovelace Brain Mapping Center at UCLA as Associate Professor of Neurology with secondary appointment in Radiology in 2010. His main interests are technical development and applications of novel quantitative functional MRI methods such as perfusion and resting state fMRI. To date, Dr. Wang has published 80 peer-reviewed papers and 10 book chapters/review articles, and has continuously been funded by NIH since 2004.



Host: Professor Krishna Nayak

More Info: http://mhi.usc.edu/medical-imaging-seminar-series/

Location: Hughes Aircraft Electrical Engineering Center (EEB) - 248

Audiences: Everyone Is Invited

Contact: Talyia Veal

Event Link: http://mhi.usc.edu/medical-imaging-seminar-series/