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Fred Grodins Distinguished Keynote Seminar
Fri, Feb 07, 2025 @ 03:00 AM - 04:00 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Shana O. Kelley, Professor of Chemistry, Biomedical Engineering, and Biochemistry & Molecular Genetics, Northwestern University, Chicago, IL
Talk Title: Continuous monitoring of protein biomarkers using implantable sensors
Abstract: To put disease-related biomarkers to work for continuous monitoring of health and disease, new high-performance technologies are needed to enable rapid and sensitive analysis of proteins and other biomarkers. Electrochemical methods providing sensitive and direct biomarker readout have attracted a great deal of attention for this application. Recently we developed reagentless sensors that are powerful detectors for in vivo protein sensing (Nature Chemistry, 2021, J. am. Chem. Soc. 2023, Angew. Chem. Intl. Ed. 2023) as well as implantable sensors for continuous monitoring (Science 2024, Nature Biomedical Engineering 2025). This talk will summarize the development of these sensors, their application to a variety of clinical problems, and the development of a range of implatable sensors for in vivo monitoring.
Biography: Dr. Shana Kelley is the President of the Chan Zuckerberg Biohub Chicago and the Neena B. Schwartz Professor at Northwestern in the Departments of Chemistry, Biomedical Engineering, and Biochemistry & Molecular Genetics. The Kelley research group has pioneered new methods for tracking molecular and cellular analytes with unprecedented sensitivity. Dr. Kelley’s work has been recognized with the ACS Inorganic Nanoscience Award, the Pittsburgh Conference Achievement Award, the Steacie Prize, an Alfred P. Sloan Research Fellowship, a Camille Dreyfus Teacher-Scholar award, a NSF CAREER Award, a Dreyfus New Faculty Award, and she was also named a “Top 100 Innovator” by MIT’s Technology Review. Kelley is also a Guggenheim Fellow, a Fellow of the Royal Society of Canada, the Canadian Academy of Health Sciences, and the American Institute of Biological and Medical Engineering. She is an elected member of the American Academy of Arts and Sciences and the National Academy of Inventors. Her work is extensively cited and she has over 80 papers cited more than 80 times. Kelley is an inventor on over 50 patents issued worldwide. She is a founder of four life sciences companies, GeneOhm Sciences (acquired by Becton Dickinson in 2005), Xagenic Inc. (acquired by General Atomics in 2017), CTRL Therapeutics (founded in 2019) and Arma Biosciences (founded in 2021).
Host: Maral Mousavi/ Peter Wang
Location: Michelson Center for Convergent Bioscience (MCB) - 102
Audiences: Everyone Is Invited
Contact: Carla Stanard