Events Calendar

Seminar in Biomedical Engineering

Speaker: Vadim Backman, PhD, Professor of Biomedical Engineering, Walter Dill Scott Professor (Northwestern University)

Talk Title: Nanoscale and functional optical imaging for colon cancer diagnostics and risk-stratification

Abstract: Initiation of carcinogenesis is accompanied by alterations in tumor microenvironment, cellular metabolism and epigenetics. Understanding these early events depends on our ability to image these subtle nanoarchitectural and functional processes. The talk discusses a suite of novel fiber-optic and in vitro diagnostic optical imaging techniques that have recently been developed to quantify intracellular and tissue morphology at the nanoscale and provide high-resolution imaging of metabolism and microangiography. The techniques have shown promise as a new platform for highly sensitive, cost-effective and non-invasive colon cancer screening and prognostication.A particularly significant application is colon cancer screening enabled by the detection of field carcinogenesis via the analysis of the nanoarchitecture of rectal cells with the objective to increase the detection rate of screen-relevant colorectal neoplasia while reducing overdiagnosis.


Biography: http://www.bme.northwestern.edu/people/faculty/backman.html

Host: Qifa Zhou/Stanley Yamashiro

Location: OHE 122

Audiences: Everyone Is Invited

Contact: Mischalgrace Diasanta