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  • Fred S. Grodins Keynote Lecture

    Mon, Oct 10, 2016 @ 03:00 PM - 04:00 PM

    Alfred E. Mann Department of Biomedical Engineering

    Receptions & Special Events

    Keynote Speaker: Dr. Roger D. Kamm
    Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering
    Massachusetts Institute of Technology
    Dept. of Biological Engineering, Dept. of Mechanical Engineering

    In Vitro Vascularized Models for Metastatic Cancer
    Over the past 10 years, our ability to realistically model the critical biological steps in disease have dramatically improved, due in part to the advances in microfluidic technologies. In particular, the capabilities to create realistic 3D microenvironments, including microvascular perfusion, have led to in vitro models for disease that offer, in many respects, considerable advantages over in vivo experiments. In this talk, I will present some recent advances in creating microvascular networks in vitro and using these to model the successive stages of metastatic cancer, especially in the context of immunotherapies and organ-specific models of metastasis.
    A primary objective of Kamm's research has been the application of fundamentals in fluid and solid mechanics to better understand essential biological and physiological phenomena. Past studies have addressed issues in the respiratory, ocular and cardiovascular systems. More recently, his attention has focused on the molecular mechanisms of cellular force sensation, cell population dynamics, and the development of new microfluidic platforms for the study of cell-cell and cell-matrix interactions, especially in the context of metastatic cancer. This cumulative work has led to over 280 refereed publications. Recognition for his contributions is reflected in Kamm's election as Fellow to AIMBE, ASME, BMES, AAAS and the IFMBE. He is also the 2010 recipient of the ASME Lissner Medal and the 2015 recipient of the Huiskes Medal, both for lifetime achievements, and is a member of the National Academy of Medicine.

    Fred S. Grodins (1915-1989), joined thef aculty at USC in 1967 as Professor of Physiology and Electrical Engineering. He established Biomedical Engineering (BME) at USC first as a Program in 1970 and subsequently as a full-fledged Department in 1976. Dr. Grodins was Professor and Chairman of BME until 1986. He remained active in research as Emeritus Professor at USC until his death in 1989.

    More Information: flyer. grodins keynote 2016 (2).pdf

    Location: Hughes Aircraft Electrical Engineering Center (EEB) - 132

    Audiences: Everyone Is Invited

    Contact: Mischalgrace Diasanta

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