Events Calendar

Electrospray and Its Applications

Daren Chen Associate Professor Department of Energy, Environmental and Chemical Engineering Washington University in St. Louis St. Louis, MO 63130 ABSTRACT:Electrospray technique (i.e., electrohydrodynamic atomization), has been proposed for many modern applications. Examples of the applications include the surface coating, agricultural treatments, emulsion, fuel spraying, micro-or nano- encapsulation, ink-jet printers, colloid micro-thrusters, electrospray mass spectrometry (ES MS) for macromolecular detection in biochemical applications, monodisperse super micro-and nono- particle generation, enhancement of droplet mixing, targeted drug delivery by inhalation, power production, and electrospray gene transfection. Among all the operational modes involved in electrospray process the cone-jet mode has been investigated and applied for the majority of above-described applications. It is because of its capability to produce un-agglomerated, monodisperse particles in the sub-micrometer and nanometer diameter ranges. Among different setups, single-capillary electrospray systems were often used in various applications. However, limitation of single-capillary electrospray is encountered in modern electrospray applications, especially in the biomedical and pharmaceutical areas. Dual-capillary electrospray (ES) technique was thus proposed to overcome the limit of a single-capillary electrospray system, thereby broadening the applications of electrospray technique. In this presentation we will first review the electrospray history and its fundamental principles, then present its modern applications in biomedical and pharmaceutical areas.

Location: Seaver Science Library SSL, Room 150

Audiences: Everyone Is Invited

Contact: April Mundy