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Quantitative Body Dynamic Contrast Enhanced MRI
Wed, Oct 19, 2011 @ 03:45 PM - 04:45 PM
Ming Hsieh Department of Electrical and Computer Engineering
Conferences, Lectures, & Seminars
Speaker: Kyunghyun (Kyung) Sung, PhD, Department of Radiology, Stanford University
Talk Title: Quantitative Body Dynamic Contrast Enhanced MRI
Abstract: Dynamic contrast enhanced MRI (DCE-MRI) detects spatial and temporal variations in signal enhancements and can offer a measure of microvascular structure and pathology. Pharmacodynamic biomarkers, provided by quantitative DCE-MRI, have a promising future to be used to monitor tumor response to treatment, but there still exist several challenges to ensure consistent and reliable quantitative DCE-MRI results across different clinical trials in oncology.
In this talk, we describe our recent technical developments to overcome these challenges by 1) improving spatial- and temporal-resolution of MRI using two novel compressed sensing methods, 2) increasing accuracy of T1 measurements with B1 inhomogeneity correction in 3T breast MRI, and 3) easily facilitating data analysis of quantitative DCE-MRI with our software developments (OsiriX plug-ins). Such developments can potentially offer more robust and reproducible measures of microvascular parameters associated with human cancers.
Biography: Kyung Hyun Sung is a Research Associate in the Department of Radiology at Stanford University. He joined the Body Magnetic Resonance (BMR) Group (directed by Brian Hargreaves), part of the Radiological Sciences Lab, after completing the PhD program (advised by Prof.Krishna Nayak) in the Electrical Engineering Department at the University of Southern California.
His research interests include Dynamic Contrast Enhanced (DCE) MRI, Compressed Sensing (CS), and Fat/Water separation.
Host: Prof. Krishna Nayak
Location: Hughes Aircraft Electrical Engineering Center (EEB) - 248
Audiences: Everyone Is Invited
Contact: Talyia Veal
