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Seminar in Biomedical Engineering
Mon, Oct 29, 2012 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: Richard W. Roberts, Ph.D., The End of Antibodies? SUPR Peptides Engineered to Target Protein Surfaces
Talk Title: TBA
Abstract: Peptides have poor biostability and natural sequences cannot readily be converted into drug-like, stable molecules. This talk will describe our efforts to adapt mRNA display to evolve highly stabilized unnatural versions of natural peptide sequences. The results of these efforts are a new class of molecules we term SUPR peptides (Scanning Unnatural Protease Resistant) that have antibody like affinity for biomolecular targets and are highly stable to proteolysis. The potential utility of these new peptides will be demonstrated in both therapeutic and diagnostic applications relating to nanomedicine and cancer biology.
Biography: Richard W. Roberts, Ph.D
Professor of Chemistry, the Mork Family Department of Chemical Engineering/Materials Science, and Biology
University of Southern California
507 RTH Mail Code 2905
Los Angeles, CA 90089-2905
Host: BME
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
