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SUNMONTUEWEDTHUFRISAT
Events for October 01, 2018
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Meet USC: Admission Presentation, Campus Tour, and Engineering TalkMon, Oct 01, 2018
Viterbi School of Engineering Undergraduate Admission
University Calendar
This half day program is designed for prospective freshmen (HS seniors and younger) and family members. Meet USC includes an information session on the University and the Admission process, a student led walking tour of campus, and a meeting with us in the Viterbi School. During the engineering session we will discuss the curriculum, research opportunities, hands-on projects, entrepreneurial support programs, and other aspects of the engineering school. Meet USC is designed to answer all of your questions about USC, the application process, and financial aid.
Reservations are required for Meet USC. This program occurs twice, once at 8:30 a.m. and again at 12:30 p.m.
Please make sure to check availability and register online for the session you wish to attend. Also, remember to list an Engineering major as your "intended major" on the webform!
RSVPLocation: Ronald Tutor Campus Center (TCC) - USC Admission Office
Audiences: Everyone Is Invited
Contact: Rebecca Kinnon
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Seminars in Biomedical Engineering
Mon, Oct 01, 2018 @ 12:30 PM - 01:50 PM
Alfred E. Mann Department of Biomedical Engineering
Conferences, Lectures, & Seminars
Speaker: B. Hyle Park, PhD, UC-Riverside, Associate Professor of Bioengineering
Talk Title: Novel OCT Imaging
Host: Qifa Zhou
Location: Olin Hall of Engineering (OHE) - 122
Audiences: Everyone Is Invited
Contact: Mischalgrace Diasanta
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Fall 2018 Joint CSC USC/CommNetS-MHI Seminar Series
Mon, Oct 01, 2018 @ 02:00 PM - 03:00 PM
Ming Hsieh Department of Electrical and Computer Engineering
Conferences, Lectures, & Seminars
Speaker: Vanessa Jonsson, City of Hope Beckman Research Institute
Talk Title: Adaptive Clinical Trial Design to Address Acquired Resistance and Therapeutic Failure
Abstract: One of the challenges facing immunotherapy as a durable therapeutic approach in a variety of metastatic cancers is the development of acquired resistance and subsequent therapeutic failure. Widespread clinical applicability of immunotherapy to solid tumors depends on the understanding of response and resistance mechanisms that are mediated by evolving interactions between the immune system and cancer cells. These dynamic interactions are increasingly being identified through longitudinal molecular analysis and immunological profiling and combine to produce an evolving measure of a patient cancer-immune status. However, cancer immune dynamics have yet to be formally quantified and studied as an evolutionary process in the context of immunotherapy clinical trials. To address this, we propose a method to integrate high dimensional, heterogeneous, longitudinal patient-derived cancer and immunological clinical data sets to identify cancer immune dynamics as well as a control theoretic method to preemptively address the onset of resistance through the prediction and synthesis of actionable immunotherapy combination strategies. We apply these methods to genomic and immunological data collected from a patient with recurrent multifocal glioblastoma that elicited a complete response and eventually recurred while enrolled in City of Hope's ongoing IL13R 2-targeting chimeric antigen (CAR) T cell trial for patients with recurrent glioblastoma. We show that dynamic treatment strategies are necessary for the control of tumors with high antigen heterogeneity and propose this as a framework by which to assess the effectiveness of adaptive clinical trial design and patient stratification for combination immunotherapy trials.
Biography: Vanessa Jonsson is an assistant research professor in the and Department of Hematology and Hematopoietic Cell Transplantation and leader of the Computational Immuno-Oncology group in the T Cell Immunotherapy Program at City of Hope. Her research program in computational biology focusses on the integration, mathematical modeling and analysis of large-scale, longitudinal genomic, transcriptomic and immunological data from clinical studies to inform and address the mechanisms of immune-resistant cancer progression. In 2015, Vanessa completed her PhD at Caltech, where she was advised by Richard Murray and David Baltimore. She is a principal investigator on a Parker Institute for Cancer Immunotherapy award to model the evolution of cancer immunity during immunotherapy trials and co-investigator on a California Institute of Regenerative Medicine (CIRM) award to study response and resistance in a phase I CAR T cell trial targeting malignant glioma. She is the recipient of the NIH and NCI career development award in clinical oncology (K12), with a focus on immuno-oncology.
Host: Mihailo Jovanovic
More Info: http://csc.usc.edu/seminars/2018Fall/jonsson.html
More Information: 18.10.01_Vanessa Jonsson CSCUSC Seminar.pdf
Location: Hughes Aircraft Electrical Engineering Center (EEB) - 132
Audiences: Everyone Is Invited
Contact: Brienne Moore
Event Link: http://csc.usc.edu/seminars/2018Fall/jonsson.html
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General Meetings
Mon, Oct 01, 2018 @ 07:00 PM - 08:00 PM
Viterbi School of Engineering Student Organizations
Student Activity
Learning how to properly vet and evaluate need areas in the healthcare system takes years of trial, error, and experience, but nobody has time for that. Swing by THH 116 this Monday to step through the notorious Stanford Biodesign process, brainstorm like the best of them, and, of course, eat!
Location: Mark Taper Hall Of Humanities (THH) - 116
Audiences: Everyone Is Invited
Contact: MEDesign USC
