Events Calendar

AME Seminar

Speaker: Pavlos P. Vlachos, Purdue

Talk Title: Fluid Mechanics in Clinical Echocardiography

Abstract: In this talk we will probe flows in cardiac disease using in-vivo measurements in clinical settings, and we will discuss how traditional experimental fluids mechanics tools can translate into clinical practice.

Flows in the cardiovascular system manifest intrinsic complexity, which is often associated with diseased states. Imaging modalities such as ultrasound/echocardiography and phase-contrast MRI provide unique opportunities and challenges for flow measurements in patients. Currently, the relationship between clinical flow measurements and clinical diagnostic parameters is qualitative, and often is reliant on heuristics and non-physical assumptions.

In this talk we will discuss how to overcome these limitations by integrating medical imaging with experimental fluid mechanics, in order to, ultimately, improve accuracy, robustness, and clinical diagnostic utility of these tools.

Specifically, we will discuss how fluid mechanics can be used in the analysis of echocardiographic imaging for heart failure. We will show an improved approach for clinical implementation of EchoPIV (echocardiographic Particle Image Velocimetry) and a new method for the velocity reconstruction of Color-Doppler flow imaging. Finally, we will present a use-case in the analysis of fetal and neonatal echocardiograms of babies born with single ventricle (hypoplastic left heart syndrome). If time permits, some additional examples of application to 4D flow MRI will be presented.

Host: AME Department

Location: James H. Zumberge Hall Of Science (ZHS) - 159

Audiences: Everyone Is Invited

Contact: Tessa Yao