Research Assistant Professor of Biomedical Engineering
Education
Biography
Dr. Longwei Liu is an Assistant Professor of Research at the Alfred E. Mann Department of Biomedical Engineering at USC Viterbi School of Engineering. Dr. Liu obtained his PhD degree in Biomedical Engineering from Tsinghua University in 2018 and completed his postdoctoral training at the University of California, San Diego (UCSD) in 2022. Dr. Liu has published eight first-author papers in Nature Materials (2017), PNAS (2020), The FASEB J (2021), Nature Communications (2021), ACS Central Science (2023) et al., three co-corresponding papers in ACS Sensors (2021), EBMO J (2022), and Clin Transl Med (2022), as well as >10 co-author papers in Nature Reviews Bioengineering (2023), Nature Materials (2022), Biomaterials (2016, 2017) et al.
Dr. Liu is the recipient of NIH K01 award, USC 2023 MHIRA award et.al.
Research Summary
Dr.Liu's long-term research career goal is to develop tools to understand better how intracellular signaling mediates intercellular communications, with a specific interest in immune-tumor cell interactions. The current research focus of Dr. Liu is to develop tools to better understand and control intracellular signaling, with a specific interest in immune-tumor cell interactions. Specifically, he develops genetically-encoded biosensors based on FRET or single fluorescent protein using a directed evolution approach and apply these biosensors to visualize molecular signals in live cells with high spatiotemporal resolution. With the guidance of these new signaling insights, he also develop novel controllable CAR-T cells for efficient immune therapy targeting solid tumors.
