Assistant Professor of Biomedical Engineering
Dr. Keyue Shen received his Bachelor of Engineering (summa cum laude) in Mechanical Engineering and Master of Science in Biophysics from Tsinghua University of China. He earned his Ph.D. degree (with Distinction) in Biomedical Engineering in the Department of Biomedical Engineering at Columbia University in 2010. He then pursued postdoctoral training in the Center for Engineering in Medicine at Harvard Medical School and Massachusetts General Hospital, where he won an MGH Fund for Medical Discovery Award. Keyue joined the Department of Biomedical Engineering at the University of Southern California in January 2015. His research interests are in developing in vitro microengineered models of cell microenvironments in immune system, cancer, and stem cell niches, for applications in immune and cancer therapeutics, as well as cell/tissue regeneration.
Dr. Shen's research group aims to develop biologically inspired in vitro platforms to capture the scale of cell signaling in tissue microenvironments from subcellular to tissue levels, and discover novel therapeutics for human diseases. We are particularly interested in developing integrated techniques for subcellular biosensing and modulation of T cell activation, and creating microfabricated models of cancer microenvironments. Our goal is to identify new targets and critical pathways in driving disease and intervention, and translate our discoveries into applications for immune and cancer therapeutics, cancer biomarker/drug development, and regenerative medicine.
Return to Faculty Directory