Alfred E.Mann Department of Biomedical Engineering - Seminar series

Speaker: Xiaoping P. Hu, Ph.D., Professor and Chair, Department of Bioengineering;Director, Center for Advanced Neuroimaging Reza Abbaschian Chair Professor University of California, Riverside

Talk Title: Some Recent Advances in MRI of Neurodegeneration

Abstract: MRI is a widely used modality in neuroimaging in both clinical medicine and research. For neurodegeneration, in addition to providing exquisite anatomic measures, MRI can assess function, connectivity, and neurobiologically relevant biomarkers such as iron and melanin.  In this talk, I will first present our work on the development of neuromelanin imaging and applying it, in conjunction with iron imaging and diffusion tensor imaging, to the diagnosis and assessment of Parkinson’s disease. Our data demonstrate that both neuromelanin and iron imaging could provide potential biomarkers for the early detection of Parkinson’s disease. Second, I will describe our more recent endeavor in imaging the integrity and structural connectivity of locus coeruleus and investigation of their relevance to aging and cognition. I will demonstrate that MR imaging of locus coeruleus could provide highly relevant measure in studying aging.

Biography: Xiaoping Hu obtained his Ph.D. in medical physics in 1988 from the University of Chicago. From 1990 to 2002, he was a faculty member at the University of Minnesota where he became a full professor in 1998. In 2002-2016, he was Professor and Georgia Research Alliance Eminent Scholar in Imaging in the Wallace H. Coulter joint department of biomedical engineering at Georgia Institute of Technology and Emory University. In July 2016, Dr. Hu joined UC Riverside as professor and chair of bioengineering and director of the center for advanced neuroimaging. Dr. Hu has worked on the development and biomedical application of magnetic resonance imaging, with an emphasis on the brain, for almost 4 decades. He has authored or co-authored 325 peer-reviewed journal articles, with a total of 33,000+ citations and an h-index of 101.  He is currently on the editorial board of Brain Connectivity and is an associate editor of Magnetic Resonance in Medicine. He is a fellow of the International Society for Magnetic Resonance in Medicine, a fellow of IEEE, a fellow of American Association for the Advancement of Sciences, a fellow of American Institute of Medical and Biological Engineering and a fellow of the International Academy of Medical and Biological Engineers. He was named Reza Abbaschian Chair in July, 2023 and promoted to distinguished professor in July, 2024.

Host: Qifa Zhou

Location: Ronald Tutor Hall of Engineering (RTH) - 109

Audiences: Everyone Is Invited

Contact: Carla Stanard

This event is open to all eligible individuals. USC Viterbi operates all of its activities consistent with the University's Notice of Non-Discrimination. Eligibility is not determined based on race, sex, ethnicity, sexual orientation, or any other prohibited factor.

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